Journal Article

Treatment of Syphilis, 1998: Nonpregnant Adults

Michael H. Augenbraun and Robert Rolfs

in Clinical Infectious Diseases

Published on behalf of Infectious Diseases Society of America

Volume 28, issue Supplement_1, pages S21-S28
Published in print January 1999 | ISSN: 1058-4838
Published online January 1999 | e-ISSN: 1537-6591 | DOI: http://dx.doi.org/10.1086/514724
Treatment of Syphilis, 1998: Nonpregnant Adults

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Questions regarding the appropriate therapy for syphilis remain, despite the many years during which this infection has been subjected to intense scientifi scrutiny. In an effort to provide guidance for the development of the 1998 sexually transmitted disease (STD) treatment guidelines of the Centers for Disease Control and Prevention (CDC), these questions were outlined and an effort to answer them was made. Articles relating to syphilis treatment published after the previous revision of the CDC STD treatment guidelines (in 1993) and by the end of 1996 were identifie with use of MEDLINE. Abstracts from relevant scientifi meetings held during that time were also examined. Reference was also made to older literature, and expert opinion was sought. Conclusions were reached and recommendations were made on the basis of published evidence wherever possible.

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Subjects: Infectious Diseases ; Immunology ; Public Health and Epidemiology ; Microbiology

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