Journal Article

Clinical Problems Posed by Multiresistant Nonfermenting Gram-Negative Pathogens

John P. Quinn

in Clinical Infectious Diseases

Published on behalf of Infectious Diseases Society of America

Volume 27, issue Supplement_1, pages S117-S124
Published in print August 1998 | ISSN: 1058-4838
Published online August 1998 | e-ISSN: 1537-6591 | DOI: http://dx.doi.org/10.1086/514912
Clinical Problems Posed by Multiresistant Nonfermenting Gram-Negative Pathogens

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In this review I will briefly survey the role of Pseudomonas aeruginosa, Acinetobacter baumanii, Stenotrophomonas maltophilia, and Burkholderia cepacia as opportunistic pathogens. A common feature of these organisms is intrinsic resistance to multiple antibiotics. All of these organisms can be recovered from the environment, commonly cause device-related infections, are often resistant to disinfectants, and have the potential to spread from patient to patient via fomites or the hands of medical personnel. Newer clinical syndromes will be emphasized, including the increasing importance of P. aeruginosa infections in patients with AIDS, as well as the role of carbapenems in selecting for A. baumanii and S. maltophilia and the unique niche of B. cepacia in patients with cystic fibrosis.

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Subjects: Infectious Diseases ; Immunology ; Public Health and Epidemiology ; Microbiology

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