Journal Article

Rapidly Evolving Hepatitis C Virus—Related Cirrhosis in a Human Immunodeficiency Virus—Infected Patient Receiving Triple Antiretroviral Therapy

Hervé Zylberberg, Gilles Pialoux, Françoise Carnot, Alain Landau, Christian Bréchot and Stanislas Pol

in Clinical Infectious Diseases

Published on behalf of Infectious Diseases Society of America

Volume 27, issue 5, pages 1255-1258
Published in print November 1998 | ISSN: 1058-4838
Published online November 1998 | e-ISSN: 1537-6591 | DOI: http://dx.doi.org/10.1086/514987
Rapidly Evolving Hepatitis C Virus—Related Cirrhosis in a Human Immunodeficiency Virus—Infected Patient Receiving Triple Antiretroviral Therapy

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Triple antiretroviral therapy combining reverse transcriptase and protease inhibitors modifies the prognosis of human immunodeficiency virus (HIV) infection, with dramatic improvement in immune status. The precise impact, if any, of anti-HIV triple therapy on hepatitis C virus (HCV) infection is unknown. We describe an unusual case of rapidly evolving HCV-related cirrhosis that paralleled restoration of immune status in an HIV-infected patient and discuss the possible link between such a severe course of hepatitis C and anti-HIV triple therapy.

Journal Article.  0 words. 

Subjects: Infectious Diseases ; Immunology ; Public Health and Epidemiology ; Microbiology

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