Journal Article

Clinical Experience and Choice of Drug Therapy for Human Immunodeficiency Virus Disease

Carol L. Brosgart, Thomas F. Mitchell, Rebecca L. Coleman, Toby Dyner, Kathryn E. Stephenson and Donald I. Abrams

in Clinical Infectious Diseases

Published on behalf of Infectious Diseases Society of America

Volume 28, issue 1, pages 14-22
Published in print January 1999 | ISSN: 1058-4838
Published online January 1999 | e-ISSN: 1537-6591 | DOI: https://dx.doi.org/10.1086/515081
Clinical Experience and Choice of Drug Therapy for Human Immunodeficiency Virus Disease

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To determine if providers experienced in the management of human immunodeficiency virus (HIV) disease preferred different treatment regimens than providers with less experience, we analyzed data from a national survey of primary care providers' preferred regimens for the management of 30 HIV-related medical conditions. We mailed questionnaires to 999 correct addresses of providers in >20 cities in the United States in May 1996. We received 524 responses (response rate, 52%). We found a statistically significant association between the number of HIV-infected patients cared for by the provider and the likelihood that the provider would report prescribing highly active antiretroviral therapy and multidrug combinations for treatment of opportunistic infections. Providers with few HIV-infected patients were substantially less likely to report using new therapeutic regimens or new diagnostic tools. We concluded that the preferred regimens of experienced providers are more likely to be consistent with the latest information on treatment for HIV disease than are those of less experienced providers.

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Subjects: Infectious Diseases ; Immunology ; Public Health and Epidemiology ; Microbiology

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