Journal Article

Relative Bradycardia Is Not a Feature of Enteric Fever in Children

Timothy M. E. Davis, Ashley E. Makepeace, Elizabeth A. Dallimore and Keng E. Choo

in Clinical Infectious Diseases

Published on behalf of Infectious Diseases Society of America

Volume 28, issue 3, pages 582-586
Published in print March 1999 | ISSN: 1058-4838
Published online March 1999 | e-ISSN: 1537-6591 | DOI: http://dx.doi.org/10.1086/515143
Relative Bradycardia Is Not a Feature of Enteric Fever in Children

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We investigated pulse-temperature relationships in 66 children with enteric fever (group 1) and in 76 with other infections (group 2). Group 1 children were older than group 2 children (mean age ± SD, 91 ± 36 vs. 66 ± 32 months, respectively; P < .001) and had mean oral temperatures ± SD similar to those of group 2 children (38.3 ± 1.0 vs. 38.3 ± 0.9°C, respectively; P > .2); however, group 1 children had lower mean baseline pulse rates ± SD than did group 2 children (119 ± 25 vs. 127 ± 28 beats/min, respectively; P < .001). In a multiple linear regression model, pulse rate was independently associated with age (inversely; P < .001) and oral temperature (positively; P < .006) but not with diagnostic group or gender (P > .5). After adjustment of the mean initial pulse rate ± SD to age of 72 months, there was no difference between group 1 and group 2 children (126 ± 24 vs. 126 ± 20 beats/min, respectively; P > .5). From 4 to 72 hours after commencement of treatment, the mean oral temperature in group 1 patients was ∼0.3°C higher than that in group 2 patients, and the age-adjusted pulse rate was 5 beats/min higher in group 1 children than in group 2 children. These data suggest that relative bradycardia is not characteristic of enteric fever in children.

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Subjects: Infectious Diseases ; Immunology ; Public Health and Epidemiology ; Microbiology

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