Journal Article

Nondispersive Infrared Spectrometry: A New Method for the Detection of <i>Helicobacter pylori</i> Infection with the <sup>13</sup>C-Urea Breath Test

Pius Hildebrand and Christoph Beglinger

in Clinical Infectious Diseases

Published on behalf of Infectious Diseases Society of America

Volume 25, issue 5, pages 1003-1005
Published in print November 1997 | ISSN: 1058-4838
Published online November 1997 | e-ISSN: 1537-6591 | DOI: http://dx.doi.org/10.1086/516069
Nondispersive Infrared Spectrometry: A New Method for the Detection of Helicobacter pylori Infection with the 13C-Urea Breath Test

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Nondispersive infrared spectrometry (NDIRS) was used to detect Helicobacter pylori infection with the 13C-urea breath test. The results were compared with those of standard isotope ratio mass spectrometry (IRMS). Both methods accurately distinguished between H. pylori-positive and H. pylori-negative individuals. The results demonstrate that NDIRS technology is accurate and therefore of equal value to standard IRMS for detection of H. pylori infection. It can be recommended for routine clinical application. As NDIRS technology is much cheaper than current IRMS machines, we consider the new method extremely useful for clinical applications.

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Subjects: Infectious Diseases ; Immunology ; Public Health and Epidemiology ; Microbiology

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