Journal Article

Klebsiella Endocarditis: Report of Two Cases and Review

Michael J. Anderson and Edward N. Janoff

in Clinical Infectious Diseases

Published on behalf of Infectious Diseases Society of America

Volume 26, issue 2, pages 468-474
Published in print February 1998 | ISSN: 1058-4838
Published online February 1998 | e-ISSN: 1537-6591 | DOI: http://dx.doi.org/10.1086/516330
Klebsiella Endocarditis: Report of Two Cases and Review

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The rarity of endocarditis due to Klebsiella species limits its recognition and awareness of its often malignant course. We describe two recent cases of Klebsiella pneumoniae endocarditis and review the clinical context and outcomes of 48 other cases reported in the literature. At our hospital, endocarditis complicated only one of 86 consecutive episodes of bacteremia due to Klebsiella species. In 22 series of endocarditis that we reviewed, Klebsiella species caused ⩽1.2% of cases of native valve endocarditis and up to 4.1% of cases of prosthetic valve endocarditis. Valves were replaced in 44% of these cases, and the mortality rate was 49% in cases for which outcome was specified. Valve replacement may be associated with improved survival. We conclude that Klebsiella species are a rare but ominous cause of complicated bacterial endocarditis that requires careful evaluation during the entire course of therapy.

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Subjects: Infectious Diseases ; Immunology ; Public Health and Epidemiology ; Microbiology

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