Journal Article

Cryptococcal Immune Reconstitution Inflammatory Syndrome following Alemtuzumab Therapy

Paul R. Ingram, Rebecca Howman, Michael F. Leahy and John R. Dyer

in Clinical Infectious Diseases

Published on behalf of Infectious Diseases Society of America

Volume 44, issue 12, pages e115-e117
Published in print June 2007 | ISSN: 1058-4838
Published online June 2007 | e-ISSN: 1537-6591 | DOI: http://dx.doi.org/10.1086/518168
Cryptococcal Immune Reconstitution Inflammatory Syndrome following Alemtuzumab Therapy

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Alemtuzumab is a lymphocyte ablative agent that may cause susceptibility to severe opportunistic infections similar to those seen in AIDS. Pathogen-specific immune reconstitution syndromes can complicate antiretroviral therapy and immune recovery in HIV-infected patients. We present the first reported case of immune reconstitution syndrome associated with T lymphocyte recovery after alemtuzumab therapy.

Journal Article.  1902 words.  Illustrated.

Subjects: Infectious Diseases ; Immunology ; Public Health and Epidemiology ; Microbiology

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