Journal Article

Clinical Management of <i>Clostridium difficile</i>-Associated Disease

Mark A. Miller

in Clinical Infectious Diseases

Published on behalf of Infectious Diseases Society of America

Volume 45, issue Supplement_2, pages S122-S128
Published in print September 2007 | ISSN: 1058-4838
Published online September 2007 | e-ISSN: 1537-6591 | DOI:
Clinical Management of Clostridium difficile-Associated Disease

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The incidence of Clostridium difficile-associated disease (CDAD) and its serious complications (including colectomy and death) have been increasing worldwide. This phenomenon is strongly associated with the appearance of a new “hypervirulent” strain in several countries. More-effective strategies are needed for the prevention and treatment of this entity. This article will review the current approaches using antimicrobials, probiotics, immunomodulation, surgery, and miscellaneous adjuvants to prevent and treat this infection.

Journal Article.  5237 words.  Illustrated.

Subjects: Infectious Diseases ; Immunology ; Public Health and Epidemiology ; Microbiology

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