Journal Article

Visceral Leishmaniasis (Kala-azar) in Solid Organ Transplantation: Report of Five Cases and Review

J. Hernández-Pérez, M. Yebra-Bango, E. Jiménez-Martínez, C. Sanz-Moreno, V. Cuervas-Mons, L. Alonso Pulpón, A. Ramos-Martínez and J. Fernández-Fernández

in Clinical Infectious Diseases

Published on behalf of Infectious Diseases Society of America

Volume 29, issue 4, pages 918-921
Published in print August 1999 | ISSN: 1058-4838
Published online August 1999 | e-ISSN: 1537-6591 | DOI: http://dx.doi.org/10.1086/520457
Visceral Leishmaniasis (Kala-azar) in Solid Organ Transplantation: Report of Five Cases and Review

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Visceral leishmaniasis is an infectious disease that occurs only rarely in recipients of solid organ grafts but is associated with an elevated mortality rate despite proper treatment. We report five cases diagnosed in our hospital. All the patients were men aged 30 to 60 years who had undergone kidney transplantation (3 patients), heart transplantation (1), or liver transplantation (1). Three of the patients died, one had multiple recurrences, and one developed post-kala-azar cutaneous leishmaniasis. We review the clinical features, treatments, and outcomes of 26 previously reported cases, pointing out the lower cure rate associated with human immunodeficiency virus infection.

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Subjects: Infectious Diseases ; Immunology ; Public Health and Epidemiology ; Microbiology

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