Journal Article

Immunologic and Clinical Responses to Highly Active Antiretroviral Therapy in Patients with HIV Infection Aged >50 Years

Lise Cuzin, Cyrille Delpierre, Stéphane Gerard, Patrice Massip and Bruno Marchou

in Clinical Infectious Diseases

Published on behalf of Infectious Diseases Society of America

Volume 45, issue 5, pages 654-657
Published in print September 2007 | ISSN: 1058-4838
Published online September 2007 | e-ISSN: 1537-6591 | DOI: https://dx.doi.org/10.1086/520652
Immunologic and Clinical Responses to Highly Active Antiretroviral Therapy in Patients with HIV Infection Aged >50 Years

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We analyzed the effect of age on highly active antiretroviral therapy efficacy and tolerance in 639 patients with human immunodeficiency virus (HIV) infection (99 of whom were aged >50 years, and 540 of whom were aged <50 years). Late testing, which was more frequent in the older age group, was the only independent factor associated with immunologic and clinical evolution of infection. Age >50 years was associated with earlier treatment discontinuation.

Journal Article.  1950 words.  Illustrated.

Subjects: Infectious Diseases ; Immunology ; Public Health and Epidemiology ; Microbiology

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