Journal Article

Assessment of Bacille Calmette-Guérin Vaccine Reaction in HIV-Exposed Thai Infants

Kulkanya Chokephaibulkit, Tawee Chotpitayasunondh, Nirun Vanprapar, Naris Waranawat, Philip A. Mock, Michelle S. McConnell, Bongkoch Jetswang, Kanchana Neeyapun, Jordan W. Tappero and Mary Culnane

in Clinical Infectious Diseases

Published on behalf of Infectious Diseases Society of America

Volume 45, issue 8, pages 1016-1018
Published in print October 2007 | ISSN: 1058-4838
Published online October 2007 | e-ISSN: 1537-6591 | DOI: http://dx.doi.org/10.1086/521929
Assessment of Bacille Calmette-Guérin Vaccine Reaction in HIV-Exposed Thai Infants

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We evaluated local reactions at 1, 2, and 4 months of age to bacille Calmette-Guérin vaccine given at birth to 1058 infants who were exposed to human immunodeficiency virus (HIV). No scar was discernible in 12 (12.4%) of 97 HIV-infected infants and 20 (2.1%) of 961 uninfected infants (relative risk, 5.9; 95% confidence interval, 3.0–11.8). This difference may reflect poorer immunogenicity in HIV-infected infants.

Journal Article.  2264 words.  Illustrated.

Subjects: Infectious Diseases ; Immunology ; Public Health and Epidemiology ; Microbiology

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