Journal Article

De Novo Autoimmune Hepatitis during Immune Reconstitution in an HIV‐Infected Patient Receiving Highly Active Antiretroviral Therapy

Jacqueline G. O'Leary, Kimon Zachary, Joseph Misdraji and Raymond T. Chung

in Clinical Infectious Diseases

Published on behalf of Infectious Diseases Society of America

Volume 46, issue 1, pages e12-e14
Published in print January 2008 | ISSN: 1058-4838
Published online January 2008 | e-ISSN: 1537-6591 | DOI: https://dx.doi.org/10.1086/524082
De Novo Autoimmune Hepatitis during Immune Reconstitution in an HIV‐Infected Patient Receiving Highly Active Antiretroviral Therapy

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Immune reconstitution inflammatory syndrome is typically seen in human immunodeficiency virus—seropositive patients who commence antiretroviral therapy. In patients who experience this syndrome, the immune system's reconstitution leads to a response directed against pathogens or autoantigens. We report, to our knowledge, the first case of autoimmune hepatitis caused by immune reconstitution.

Journal Article.  1554 words.  Illustrated.

Subjects: Infectious Diseases ; Immunology ; Public Health and Epidemiology ; Microbiology

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