Journal Article

Low Positive Predictive Value of a Nucleic Acid Amplification Test for Nongenital <i>Neisseria gonorrhoeae</i> Infection in Homosexual Men

Leon P. McNally, David J. Templeton, Fengyi Jin, Andrew E. Grulich, Basil Donovan, David M. Whiley and Philip H. Cunningham

in Clinical Infectious Diseases

Published on behalf of Infectious Diseases Society of America

Volume 47, issue 2, pages e25-e27
Published in print July 2008 | ISSN: 1058-4838
Published online July 2008 | e-ISSN: 1537-6591 | DOI: http://dx.doi.org/10.1086/589299
Low Positive Predictive Value of a Nucleic Acid Amplification Test for Nongenital Neisseria gonorrhoeae Infection in Homosexual Men

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The diagnosis of nongenital Neisseria gonorrhoeae infection by the Becton Dickinson ProbeTec ET Chlamydia trachomatis and N. gonorrhoeae Amplified DNA assay had low positive predictive value among an Australian communitybased sample of homosexual men. Only 30.4% of oropharyngeal samples and 73.7% of anorectal samples were positive for N. gonorrhoeae by the porA assay. The accuracy of nucleic acid amplification tests in this context is compromised without supplemental testing.

Journal Article.  2321 words. 

Subjects: Infectious Diseases ; Immunology ; Public Health and Epidemiology ; Microbiology

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