Journal Article

Workshop on HIV Infection and Aging: What Is Known and Future Research Directions

Kevin P. High, Rita B. Effros, Courtney V. Fletcher, Kelly Gebo, Jeffrey B. Halter, William R. Hazzard, Frances McFarland Horne, Robin E. Huebner, Edward N. Janoff, Amy C. Justice, Daniel Kuritzkes, Susan G. Nayfield, Susan F. Plaeger, Kenneth E. Schmader, John R. Ashworth, Christine Campanelli, Charles P. Clayton, Beth Rada, Nancy F. Woolard and Kevin P. High

in Clinical Infectious Diseases

Published on behalf of Infectious Diseases Society of America

Volume 47, issue 4, pages 542-553
Published in print August 2008 | ISSN: 1058-4838
Published online August 2008 | e-ISSN: 1537-6591 | DOI: http://dx.doi.org/10.1086/590150
Workshop on HIV Infection and Aging: What Is Known and Future Research Directions

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Highly active antiretroviral treatment has resulted in dramatically increased life expectancy among patients with HIV infection who are now aging while receiving treatment and are at risk of developing chronic diseases associated with advanced age. Similarities between aging and the courses of human immunodeficiency virus (HIV) infection and acquired immunodeficiency syndrome suggest that HIV infection compresses the aging process, perhaps accelerating comorbidities and frailty. In a workshop organized by the Association of Specialty Professors, the Infectious Diseases Society of America, the HIV Medical Association, the National Institute on Aging, and the National Institute on Allergy and Infectious Diseases, researchers in infectious diseases, geriatrics, immunology, and gerontology met to review what is known about HIV infection and aging, to identify research gaps, and to suggest high priority topics for future research. Answers to the questions posed are likely to help prioritize and balance strategies to slow the progression of HIV infection, to address comorbidities and drug toxicity, and to enhance understanding about both HIV infection and aging.

Journal Article.  8811 words.  Illustrated.

Subjects: Infectious Diseases ; Immunology ; Public Health and Epidemiology ; Microbiology

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