Journal Article

Hodgkin Lymphoma–Associated Hemophagocytic Syndrome: A Disorder Strongly Correlated with Epstein-Barr Virus

Fanny Mánard, Caroline Besson, Patricia Rincá, Olivier Lambotte, Thierry Lazure, Danielle Canioni, Olivier Hermine, Pierre Brousset, Antoine Martin, Philippe Gaulard, Martine Raphaël and Claire Larroche

in Clinical Infectious Diseases

Published on behalf of Infectious Diseases Society of America

Volume 47, issue 4, pages 531-534
Published in print August 2008 | ISSN: 1058-4838
Published online August 2008 | e-ISSN: 1537-6591 | DOI: http://dx.doi.org/10.1086/590152
Hodgkin Lymphoma–Associated Hemophagocytic Syndrome: A Disorder Strongly Correlated with Epstein-Barr Virus

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The retrospective study of 34 patients with Hodgkin lymphoma–associated hemophagocytic syndrome led us to define this association as a specific disorder. Its characteristics are male predominance (male-to-female sex ratio, 3.3∷1), immunodeficiency-like histological features (lymphocyte depletion, 45% of cases; mixed cellularity Hodgkin lymphoma subtype, 40%), and strong association with Epstein-Barr virus (94%).

Journal Article.  2230 words.  Illustrated.

Subjects: Infectious Diseases ; Immunology ; Public Health and Epidemiology ; Microbiology

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