Journal Article

Sexual Risk Factors and Bacterial Vaginosis: A Systematic Review and Meta-Analysis

Katherine A. Fethers, Christopher K. Fairley, Jane S. Hocking, Lyle C. Gurrin and Catriona S. Bradshaw

in Clinical Infectious Diseases

Published on behalf of Infectious Diseases Society of America

Volume 47, issue 11, pages 1426-1435
Published in print December 2008 | ISSN: 1058-4838
Published online December 2008 | e-ISSN: 1537-6591 | DOI: https://dx.doi.org/10.1086/592974
Sexual Risk Factors and Bacterial Vaginosis: A Systematic Review and Meta-Analysis

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We performed a systematic review and meta-analysis of the association between sexual risk factors and bacterial vaginosis (BV). Forty-three studies reported new or multiple sexual partners and condom use relative to prevalent, incident, or recurrent BV. The summary estimate of the relative risk for the association between BV new or multiple male partners was 1.6 (95% confidence interval, 1.5–1.8), between BV and any female partners was 2.0 (95% confidence interval, 1.7–2.3), and between BV and condom use was 0.8 (95% confidence interval, 0.8–0.9). This review is the first to summarize available observational data for BV. It shows that BV is significantly associated with sexual contact with new and multiple male and female partners and that decreasing the number of unprotected sexual encounters may reduce incident and recurrent infection. Investigation of sexual transmission of BV is limited by the absence of a clear microbiological etiology; however, we have shown that the epidemiological profile of BV is similar to that of established sexually transmitted infections.

Journal Article.  5737 words.  Illustrated.

Subjects: Infectious Diseases ; Immunology ; Public Health and Epidemiology ; Microbiology

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