Journal Article

Linear Erosive Herpes Simplex Virus Infection in Immunocompromised Patients: The “Knife-Cut Sign”

Jocelyn A. Lieb, Stacey Brisman, Sara Herman, Jennifer MacGregor and Marc E. Grossman

in Clinical Infectious Diseases

Published on behalf of Infectious Diseases Society of America

Volume 47, issue 11, pages 1440-1441
Published in print December 2008 | ISSN: 1058-4838
Published online December 2008 | e-ISSN: 1537-6591 | DOI: http://dx.doi.org/10.1086/592976
Linear Erosive Herpes Simplex Virus Infection in Immunocompromised Patients: The “Knife-Cut Sign”

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Herpes simplex virus in immunocompromised patients may be misdiagnosed because of its atypical presentation. We present 3 cases of herpes simplex virus presenting as intertriginous fissures similar to the “knife-cut” ulcers associated with metastatic Crohn's disease. Our experience suggests that intertriginous fissures due to herpes simplex virus are recognizable patterns of viral infections in immunocompromised hosts.

Journal Article.  1069 words.  Illustrated.

Subjects: Infectious Diseases ; Immunology ; Public Health and Epidemiology ; Microbiology

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