Journal Article

Severe Postvaccinia Encephalitis with Acute Disseminated Encephalomyelitis: Recovery with Early Intravenous Immunoglobulin, High-Dose Steroids, and Vaccinia Immunoglobulin

Cornelius N. Van Dam, Samina Syed, Joseph J. Eron, Matthew Ostrander, Renata J. M. Engler, Inger Damon, Jay R. Montgomery, Suxiang Tong, Adaora A. Adimora, Kevin A. Kahn, Susan Ruone, Larry Anderson and David J. Weber

in Clinical Infectious Diseases

Published on behalf of Infectious Diseases Society of America

Volume 48, issue 4, pages e47-e49
Published in print February 2009 | ISSN: 1058-4838
Published online February 2009 | e-ISSN: 1537-6591 | DOI: http://dx.doi.org/10.1086/596553
Severe Postvaccinia Encephalitis with Acute Disseminated Encephalomyelitis: Recovery with Early Intravenous Immunoglobulin, High-Dose Steroids, and Vaccinia Immunoglobulin

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We report the second case of severe postvaccinial encephalitis with acute disseminated encephalomyelitis since smallpox vaccination was reintroduced in 2002. Both affected patients responded dramatically with early intervention of intravenous immunoglobulin. Our patient, who also received concurrent vaccinia immunoglobulin and corticosteroids, demonstrated full recovery.

Journal Article.  2194 words.  Illustrated.

Subjects: Infectious Diseases ; Immunology ; Public Health and Epidemiology ; Microbiology

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