Journal Article

Multidrug-Resistant Tuberculosis (TB) Resistant to Fluoroquinolones and Streptomycin but Susceptible to Second-Line Injection Therapy Has a Better Prognosis than Extensively Drug-Resistant TB

Edward D. Chan, Matthew J. Strand and Michael D. Iseman

in Clinical Infectious Diseases

Published on behalf of Infectious Diseases Society of America

Volume 48, issue 5, pages e50-e52
Published in print March 2009 | ISSN: 1058-4838
Published online March 2009 | e-ISSN: 1537-6591 | DOI: http://dx.doi.org/10.1086/597010
Multidrug-Resistant Tuberculosis (TB) Resistant to Fluoroquinolones and Streptomycin but Susceptible to Second-Line Injection Therapy Has a Better Prognosis than Extensively Drug-Resistant TB

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Multidrug-resistant tuberculosis (TB) strains resistant to the fluoroquinolones and streptomycin but susceptible to second-line injection treatment would not be defined as extensively drug-resistant TB. In a cohort of 174 patients with multidrug-resistant TB, we demonstrated that 12 patients with multidrug-resistant TB strains resistant to the fluoroquinolones and streptomycin had significantly better initial and long-term outcomes, compared with 10 patients with extensively drug-resistant TB.

Journal Article.  1541 words.  Illustrated.

Subjects: Infectious Diseases ; Immunology ; Public Health and Epidemiology ; Microbiology

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