Journal Article

Spatial Patterns in Discordant Diagnostic Test Results for Chagas Disease: Links to Transmission Hotspots

Michael Z. Levy, Natalie M. Bowman, Vivian Kawai, Joshua B. Plotkin, Lance A. Waller, Lilia Cabrera, Frank Steurer, Amy E. Seitz, Viviana V. Pinedo Cancino, Juan Geny Cornejo del Carpio, Eleazar Cordova Benzaquen, F. Ellis McKenzie, James H. Maguire, Robert H. Gilman and Caryn Bern

in Clinical Infectious Diseases

Published on behalf of Infectious Diseases Society of America

Volume 48, issue 8, pages 1104-1106
Published in print April 2009 | ISSN: 1058-4838
Published online April 2009 | e-ISSN: 1537-6591 | DOI: https://dx.doi.org/10.1086/597464
Spatial Patterns in Discordant Diagnostic Test Results for Chagas Disease: Links to Transmission Hotspots

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Diagnosis of Chagas disease is hindered by discordance between screening and confirmatory test results for Trypanosoma cruzi infection. In periurban Arequipa, Peru, spatial analysis revealed that individuals with discordant test results are spatially clustered in hotspots of T. cruzi transmission, suggesting that discordant results likely represent true infections in this setting.

Journal Article.  2112 words.  Illustrated.

Subjects: Infectious Diseases ; Immunology ; Public Health and Epidemiology ; Microbiology

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