Journal Article

Decreased Viral Load and Symptoms of Polyomavirus-Associated Chronic Interstitial Cystitis after Intravesical Cidofovir Treatment

Damon P. Eisen, Ian R. Fraser, Linda M. Sung, Moira Finlay, Scott Bowden and Helen O'Connell

in Clinical Infectious Diseases

Published on behalf of Infectious Diseases Society of America

Volume 48, issue 9, pages e86-e88
Published in print May 2009 | ISSN: 1058-4838
Published online May 2009 | e-ISSN: 1537-6591 | DOI: http://dx.doi.org/10.1086/597827
Decreased Viral Load and Symptoms of Polyomavirus-Associated Chronic Interstitial Cystitis after Intravesical Cidofovir Treatment

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Interstitial cystitis causes disabling bladder pain and is usually diagnosed in the absence of infection. We describe a patient with interstitial cystitis who had high urinary levels of polyomavirus that decreased dramatically after initiation of intravesical cidofovir treatment; the patient also showed substantial improvement in symptoms. Another patient had milder symptoms of cystitis and intermittent polyomavirus shedding. Polyomaviruses, particularly BK virus, may cause some cases of interstitial cystitis.

Journal Article.  1937 words.  Illustrated.

Subjects: Infectious Diseases ; Immunology ; Public Health and Epidemiology ; Microbiology

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