Journal Article

Adalimumab Treatment of Life-Threatening Tuberculosis

Robert S. Wallis, Cloete van Vuuren and Samantha Potgieter

in Clinical Infectious Diseases

Published on behalf of Infectious Diseases Society of America

Volume 48, issue 10, pages 1429-1432
Published in print May 2009 | ISSN: 1058-4838
Published online May 2009 | e-ISSN: 1537-6591 | DOI: http://dx.doi.org/10.1086/598504
Adalimumab Treatment of Life-Threatening Tuberculosis

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Most guidelines call for the discontinuation of treatment with tumor necrosis factor blockers in patients who develop tuberculosis. We report a case of life-threatening tuberculosis paradoxical reaction involving the lungs caused by withdrawal of the anti–tumor necrosis factor antibody adalimumab. Clinical improvement occurred only after resumption of adalimumab treatment.

Journal Article.  2331 words.  Illustrated.

Subjects: Infectious Diseases ; Immunology ; Public Health and Epidemiology ; Microbiology

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