Journal Article

Kawasaki Syndrome-Like Illness Associated with Infection Caused by Enterotoxin B-Secreting <i>Staphylococcus aureus</i>

Mary Hall, Laura Hoyt, Patricia Ferrieri, Patrick M. Schlievert and Hal B. Jenson

in Clinical Infectious Diseases

Published on behalf of Infectious Diseases Society of America

Volume 29, issue 3, pages 586-589
Published in print September 1999 | ISSN: 1058-4838
Published online September 1999 | e-ISSN: 1537-6591 | DOI: http://dx.doi.org/10.1086/598638
Kawasaki Syndrome-Like Illness Associated with Infection Caused by Enterotoxin B-Secreting Staphylococcus aureus

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Two children had symptoms and clinical signs that were characteristic of the diagnostic criteria for Kawasaki syndrome, temporally associated with Staphylococcus aureus bacteremia. One child initially had focal osteomyelitis that was evident clinically and radiographically, and radiographic evidence of multifocal osteomyelitis was noted at follow-up. The blood-borne S. aureus isolates from these two patients secreted staphylococcal enterotoxin B and were negative for toxic shock syndrome toxin. Staphylococcal and streptococcal superantigens may playa role in the pathogenesis of some cases of Kawasaki syndrome or Kawasaki syndrome-like illness.

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Subjects: Infectious Diseases ; Immunology ; Public Health and Epidemiology ; Microbiology

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