Journal Article

Self-Reported Bacterial Infections Among Women with or at Risk for Human Immunodeficiency Virus Infection

T. P. Flanigan, J. W. Hogan, D. Smith, E. Schoenbaum, D. Vlahov, P. Schuman and K. Mayer

in Clinical Infectious Diseases

Published on behalf of Infectious Diseases Society of America

Volume 29, issue 3, pages 608-612
Published in print September 1999 | ISSN: 1058-4838
Published online September 1999 | e-ISSN: 1537-6591 | DOI: http://dx.doi.org/10.1086/598641
Self-Reported Bacterial Infections Among Women with or at Risk for Human Immunodeficiency Virus Infection

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Bacterial infections are a major cause of morbidity and mortality in persons with human immunodeficiency virus (HIV) infection, particularly women. We performed a cross-sectional analysis of a history of bacterial infections among 1,310 women with or at risk for HIV infection. HIV-seropositive women were significantly more likely than seronegative women to report recent and lifetime histories of bacterial infection, even after history of injection drug use since 1977 was adjusted for; this included recent pneumonia (odds ratio [OR), 3.2; 95% confidence interval [CI], 1.5–6.6), sinusitis (OR, 1.4; 95% CI, 1.0–2.0), and urinary tract infection (OR, 1.5; 95% CI, 1.1–2.1). Compared with HIV-negative women, women with CD4 cell counts of <200 were about eight times more likely to report recent pneumonia (OR, 7.8; 95% CI, 3.4–17.7); those with CD4 cell counts of 200-500 were almost three times more likely to do so (OR, 2.6; CI, 1.2–5.7). Logistic regression analysis revealed that only CD4 cell category and a recent history of smoking had a significant relationship to self-reported pneumonia.

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Subjects: Infectious Diseases ; Immunology ; Public Health and Epidemiology ; Microbiology

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