Journal Article

Treatment Responses in Antiretroviral Treatment-Naive Premenopausal and Postmenopausal HIV-1-Infected Women: An Analysis from AIDS Clinical Trials Group Studies

Kristine B. Patterson, Susan E. Cohn, Jennifer Uyanik, Michael Hughes, Marlene Smurzynski and Joseph J. Eron

in Clinical Infectious Diseases

Published on behalf of Infectious Diseases Society of America

Volume 49, issue 3, pages 473-476
Published in print August 2009 | ISSN: 1058-4838
Published online August 2009 | e-ISSN: 1537-6591 | DOI: https://dx.doi.org/10.1086/600398
Treatment Responses in Antiretroviral Treatment-Naive Premenopausal and Postmenopausal HIV-1-Infected Women: An Analysis from AIDS Clinical Trials Group Studies

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Menopause may affect antiretroviral treatment (ART) response. Immunologic and virologic responses to ART were compared in 220 premenopausal and 47 postmenopausal women enrolled in 2 studies involving ART-naive persons. Changes in CD4 counts or human immunodeficiency virus type 1 RNA levels were similar at 24, 48, and 96 weeks after treatment initiation. ART-naive women should respond to ART regardless of menopausal status.

Journal Article.  2312 words.  Illustrated.

Subjects: Infectious Diseases ; Immunology ; Public Health and Epidemiology ; Microbiology

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