Journal Article

Outbreak of Life-Threatening Coxsackievirus B1 Myocarditis in Neonates

Natasha A. Verma, Xiaotian T. Zheng, Michelle U. Harris, Sandra B. Cadichon, Hector Melin-Aldana, Nino Khetsuriani, M. Steven Oberste and Stanford T. Shulman

in Clinical Infectious Diseases

Published on behalf of Infectious Diseases Society of America

Volume 49, issue 5, pages 759-763
Published in print September 2009 | ISSN: 1058-4838
Published online September 2009 | e-ISSN: 1537-6591 | DOI: http://dx.doi.org/10.1086/605089
Outbreak of Life-Threatening Coxsackievirus B1 Myocarditis in Neonates

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In the summer and fall of 2007, we observed a unique cluster of cases of severe coxsackievirus B1 (CVB1) infection among Chicago area neonates. Eight neonates had closely related strains of CVB1 that were typed at the Centers of Disease Control and Prevention; 2 other neonates had CVB infections, 1 of which was further identified as serotype CVB1. All had severe myocarditis; 1 neonate underwent heart transplantation, and 1 died of severe left ventricular dysfunction.

Journal Article.  2407 words.  Illustrated.

Subjects: Infectious Diseases ; Immunology ; Public Health and Epidemiology ; Microbiology

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