Journal Article

Recurrent, Multifocal <i>Mycobacterium avium-intercellulare</i> Infection in a Patient with Interferon-γ Autoantibody

N. Baerlecken, R. Jacobs, M. Stoll, R. E. Schmidt and T. Witte

in Clinical Infectious Diseases

Published on behalf of Infectious Diseases Society of America

Volume 49, issue 7, pages e76-e78
Published in print October 2009 | ISSN: 1058-4838
Published online October 2009 | e-ISSN: 1537-6591 | DOI: http://dx.doi.org/10.1086/605581
Recurrent, Multifocal Mycobacterium avium-intercellulare Infection in a Patient with Interferon-γ Autoantibody

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We describe a patient who experienced severe osteomyelitis because of Mycobacterium avium-intercellulare infection and high-titered autoantibodies against interferon-γ. In addition to antimycobacterial chemotherapy, we treated our patient with plasmapheresis and cyclophosphamide. The treatment induced a remission after 3 years of follow-up.

Journal Article.  1391 words.  Illustrated.

Subjects: Infectious Diseases ; Immunology ; Public Health and Epidemiology ; Microbiology

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