Journal Article

Molecular and Clinical Assessment in the Treatment of AIDS Kaposi Sarcoma with Valproic Acid

Maryjo Lechowicz, Dirk P. Dittmer, Jeannette Y. Lee, Susan E. Krown, William Wachsman, David Aboulafia, Bruce J. Dezube, Lee Ratner, Jonathan Said and Richard F. Ambinder

in Clinical Infectious Diseases

Published on behalf of Infectious Diseases Society of America

Volume 49, issue 12, pages 1946-1946
Published in print December 2009 | ISSN: 1058-4838
Published online December 2009 | e-ISSN: 1537-6591 | DOI: http://dx.doi.org/10.1086/648447
Molecular and Clinical Assessment in the Treatment of AIDS Kaposi Sarcoma with Valproic Acid

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The AIDS Malignancy Consortium undertook a pilot trial of valproic acid among patients with AIDS-associated Kaposi sarcoma (KS). Treatment was associated with low toxicity, but the KS clinical response and KS herpesvirus lytic induction rates were not sufficiently high to meet predefined criteria for efficacy.

Journal Article.  2002 words.  Illustrated.

Subjects: Infectious Diseases ; Immunology ; Public Health and Epidemiology ; Microbiology

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