Journal Article

Miltefosine Treatment of <i>Leishmania major</i> Infection: An Observational Study Involving Dutch Military Personnel Returning from Northern Afghanistan

P.P.A.M. van Thiel, T. Leenstra, P.A. Kager, H.J. de Vries, M. van Vugt, W.F. van der Meide, A. Bart, J.E. Zeegelaar, A. van der Sluis, H.D.F.H. Schallig, T. van Gool, W.R. Faber and P.J. de Vries

in Clinical Infectious Diseases

Published on behalf of Infectious Diseases Society of America

Volume 50, issue 1, pages 80-83
Published in print January 2010 | ISSN: 1058-4838
Published online January 2010 | e-ISSN: 1537-6591 | DOI: http://dx.doi.org/10.1086/648726
Miltefosine Treatment of Leishmania major Infection: An Observational Study Involving Dutch Military Personnel Returning from Northern Afghanistan

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In a retrospective, observational study involving 34 patients with Leishmania major infection, 31 of whom had experienced unsuccessful treatment with intralesional antimony (ilSbv), miltefosine proved effective. Thirty patients experienced cure after receipt of miltefosine, 3 after receipt of additional ilSbv, and 1 after 28 daily intravenous injections of antimony. Temporary diminution of ejaculate volume was reported by 21 patients.

Journal Article.  2188 words.  Illustrated.

Subjects: Infectious Diseases ; Immunology ; Public Health and Epidemiology ; Microbiology

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