Journal Article

CD4 T Cell Count Reconstitution in HIV Controllers after Highly Active Antiretroviral Therapy

Jason F. Okulicz, Greg A. Grandits, Amy C. Weintrob, Michael L. Landrum, Anuradha Ganesan, Nancy F. Crum-Cianflone, Brian K. Agan and Vincent C. Marconi

in Clinical Infectious Diseases

Published on behalf of Infectious Diseases Society of America

Volume 50, issue 8, pages 1187-1191
Published in print April 2010 | ISSN: 1058-4838
Published online April 2010 | e-ISSN: 1537-6591 | DOI: http://dx.doi.org/10.1086/651421
CD4 T Cell Count Reconstitution in HIV Controllers after Highly Active Antiretroviral Therapy

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Sixty-two human immunodeficiency virus (HIV) controllers (6 elite and 56 viremic controllers) in the US Military Department of Defense HIV Natural History Study cohort initiated highly active antiretroviral therapy (HAART) and achieved statistically significant mean CD4 cell count increases, although the gains were lower than those in treated noncontrollers. HIV controllers experienced CD4 cell count reconstitution with HAART regardless of pretherapy viral load, including patients with undetectable viral loads at HAART initiation.

Journal Article.  2356 words.  Illustrated.

Subjects: Infectious Diseases ; Immunology ; Public Health and Epidemiology ; Microbiology

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