Journal Article

Serologic Response to Hepatitis B Vaccination in HIV-Infected Patients with Isolated Positivity for Antibodies to Hepatitis B Core Antigen

Catherine Chakvetadze, Firouzé Bani-Sadr, Catherine Le Pendeven, François-Xavier Lescure, Camille Fontaine, Tatiana Galperine, Laurence Slama, Philippe Bonnard, Philippe Mariot, Patrick Soussan and Gilles Pialoux

in Clinical Infectious Diseases

Published on behalf of Infectious Diseases Society of America

Volume 50, issue 8, pages 1184-1186
Published in print April 2010 | ISSN: 1058-4838
Published online April 2010 | e-ISSN: 1537-6591 | DOI: http://dx.doi.org/10.1086/651422
Serologic Response to Hepatitis B Vaccination in HIV-Infected Patients with Isolated Positivity for Antibodies to Hepatitis B Core Antigen

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We assessed the safety and immunogenicity of hepatitis B vaccination among 40 human immunodeficiency virus-infected patients with isolated positivity for antibodies to hepatitis B core antigen. No baseline factors were found to be predictive of an anamnestic response, which occurred in 32.5% of the patients. The overall response rate among patients without an anamnestic response was 74.0% after 3–6 vaccine doses.

Journal Article.  2233 words.  Illustrated.

Subjects: Infectious Diseases ; Immunology ; Public Health and Epidemiology ; Microbiology

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