Journal Article

Predictors of Death after <i>Clostridium difficile</i> Infection: A Report on 128 Strain-Typed Cases from a Teaching Hospital in the United Kingdom

Vhairi Wilson, Liz Cheek, Giovanni Satta, Karen Walker Bone, Marc Cubbon, Diane Citron, Dale N. Gerding and Martin J. Llewelyn

in Clinical Infectious Diseases

Published on behalf of Infectious Diseases Society of America

Volume 50, issue 12, pages e77-e81
Published in print June 2010 | ISSN: 1058-4838
Published online June 2010 | e-ISSN: 1537-6591 | DOI: http://dx.doi.org/10.1086/653012
Predictors of Death after Clostridium difficile Infection: A Report on 128 Strain-Typed Cases from a Teaching Hospital in the United Kingdom

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We assessed the relationship between strain type, clinical factors, and outcome in 128 patients with Clostridium difficile infection. Strain type was not associated with any outcome measure. On multivariate analysis, ischemic heart disease and hypoalbuminemia predicted death. Metronidazole treatment in severe disease was associated with a higher rate of treatment failure and death.

Journal Article.  2156 words.  Illustrated.

Subjects: Infectious Diseases ; Immunology ; Public Health and Epidemiology ; Microbiology

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