Journal Article

Frequency of Occult High-Grade Squamous Intraepithelial Neoplasia and Invasive Cancer within Anal Condylomata in Men Who Have Sex with Men

Hans P. Schlecht, Dana K. Fugelso, Ryan K. Murphy, Katiri T. Wagner, John P. Doweiko, JoAnn Proper, Bruce J. Dezube and Lori A. Panther

in Clinical Infectious Diseases

Published on behalf of Infectious Diseases Society of America

Volume 51, issue 1, pages 107-110
Published in print July 2010 | ISSN: 1058-4838
Published online July 2010 | e-ISSN: 1537-6591 | DOI: http://dx.doi.org/10.1086/653426
Frequency of Occult High-Grade Squamous Intraepithelial Neoplasia and Invasive Cancer within Anal Condylomata in Men Who Have Sex with Men

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Human papillomavirus causes anal condylomata, high-grade anal intraepithelial neoplasia, and anal squamous cell cancer. We found high-grade intraepithelial neoplasia or squamous cell cancer in 75 (47%) of 159 HIV-seropositive men who have sex with men (MSM) and in 42 (26%) of 160 HIVseronegative MSM with anal condylomata meriting surgery (P<.001, determined by use of the χ2 test). Anal condylomata in MSM often harbor high-grade intraepithelial neoplasia and squamous cell cancer.

Journal Article.  2216 words.  Illustrated.

Subjects: Infectious Diseases ; Immunology ; Public Health and Epidemiology ; Microbiology

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