Journal Article

Anisakidosis: Perils of the Deep

Natasha S. Hochberg, Davidson H. Hamer, James M. Hughes and Mary E. Wilson

in Clinical Infectious Diseases

Published on behalf of Infectious Diseases Society of America

Volume 51, issue 7, pages 806-812
Published in print October 2010 | ISSN: 1058-4838
Published online October 2010 | e-ISSN: 1537-6591 | DOI:
Anisakidosis: Perils of the Deep

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Anisakidosis, human infection with nematodes of the family Anisakidae, is caused most commonly by Anisakis simplex and Pseudoterranova decipiens. Acquired by the consumption of raw or undercooked marine fish or squid, anisakidosis occurs where such dietary customs are practiced, including Japan, coastal regions of Europe, and the United States. Severe epigastric pain, resulting from larval invasion of the gastric mucosa, characterizes gastric anisakidosis; other syndromes are intestinal and ectopic. Allergic anisakidosis is a frequent cause of foodborne allergies in areas with heavy fish consumption or occupational exposure. Diagnosis and treatment of gastric disease is usually made by a compatible dietary history and visualization and removal of the larva(e) on endoscopy; serologic testing for anti—A. simplex immunoglobulin E can aid in the diagnosis of intestinal, ectopic and allergic disease. Intestinal and/or ectopic cases may require surgical removal; albendazole has been used occasionally. Preventive measures include adequately freezing or cooking fish.

The ocean is a wilderness reaching round the globe, wilder than a Bengal jungle, and fuller of monsters.

—Henry David Thoreau, Cape Cod [1, p 188]

Journal Article.  3976 words.  Illustrated.

Subjects: Infectious Diseases ; Immunology ; Public Health and Epidemiology ; Microbiology

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