Journal Article

AIDS-Associated <i>Cryptococcus neoformans</i> and <i>Penicillium marneffei</i> Coinfection: A Therapeutic Dilemma in Resource-Limited Settings

Thuy Le, Tran Thi Hong Chau, Ngo Thi Kim Cuc, Pham Si Lam, Tran Phu Manh Sieu, Cecilia M. Shikuma and Jeremy N. Day

in Clinical Infectious Diseases

Published on behalf of Infectious Diseases Society of America

Volume 51, issue 9, pages e65-e68
Published in print November 2010 | ISSN: 1058-4838
Published online November 2010 | e-ISSN: 1537-6591 | DOI: http://dx.doi.org/10.1086/656685
AIDS-Associated Cryptococcus neoformans and Penicillium marneffei Coinfection: A Therapeutic Dilemma in Resource-Limited Settings

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AIDS-associated Cryptococcus neoformans and Penicillium marneffei coinfection has not been adequately studied and poses unique therapeutic challenges in resource-limited settings. Itraconazole poorly penetrates the central nervous system, whereas fluconazole has poor activity against P. marneffei. We prospectively report management of 1 patient and retrospectively review 7 coinfection cases from Vietnam.

Journal Article.  2152 words.  Illustrated.

Subjects: Infectious Diseases ; Immunology ; Public Health and Epidemiology ; Microbiology

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