Research Agenda for Schizophrenia

Edited by Dwight L. Evans, Edna B. Foa, Raquel E. Gur, Herbert Hendin, Charles P. O'Brien, Martin E.P. Seligman and B. Timothy Walsh

in Treating and Preventing Adolescent Mental Health Disorders

Published on behalf of Oxford University Press

Published in print June 2005 | ISBN: 9780195173642
Published online August 2012 | e-ISBN: 9780199951024 | DOI:

Series: Adolescent Mental Health Initiative

 Research Agenda for Schizophrenia

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  • Psychiatry
  • Child and Adolescent Psychiatry


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We have learned a great deal about the early course of schizophrenia during the past two decades, leading to therapeutic optimism. However, several key areas of research continue to be a priority. First, we need to identify specific clinical characteristics in the premorbid and prodromal phases that can help us predict the individuals at a high risk for developing psychosis. Second, we do not know how to prospectively identify the early beginnings of the psychotic illness with an adequate degree of reliability to be able to intervene early. We also need to better understand the pathways to care for these patients. Educating the public and health care providers in early signs and symptoms can reduce the delay in care. Third, we need to further clarify the clinical features in the first psychotic episode that can help us predict subsequent illness course. Finally, we need to better understand the neurodevelopmental and neurodeteriorative processes that may underlie both the emergence and the subsequent course of the first psychotic episode.

Chapter.  623 words. 

Subjects: Psychiatry ; Child and Adolescent Psychiatry

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