Chapter

Contribution of experimental studies to understanding the pathophysiology of migraine

J.W. Lance, G.A. Lambert, P.J. Goadsby and A.S. Zagami

in Migraine: A Spectrum of Ideas

Published in print March 1990 | ISBN: 9780192618108
Published online March 2012 | e-ISBN: 9780191724305 | DOI: http://dx.doi.org/10.1093/acprof:oso/9780192618108.003.0003
Contribution of experimental studies to understanding the pathophysiology of migraine

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For any hypothesis to be truly satisfying, it must be compatible with all the known facts. The manifestations of migraine are so diverse that one must resist the temptation to seize on some and reject others in an attempt to justify a tenuous theory. Certain symptoms that can be recognized within the conceptual framework of migraine may be present in some episodes and not others, and may recur in certain phases of each attack but not in others. Each of these symptoms or groups of symptoms may have a different neurovascular basis.

Keywords: experimental studies; pathophysiology; migraine; symptoms; neurovascular function; migraine attack

Chapter.  8413 words.  Illustrated.

Subjects: Neuroscience

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