Chapter

The biochemical basis of migraine predisposition

Vivette Glover and Merton Sandler

in Migraine: A Spectrum of Ideas

Published in print March 1990 | ISBN: 9780192618108
Published online March 2012 | e-ISBN: 9780191724305 | DOI: http://dx.doi.org/10.1093/acprof:oso/9780192618108.003.0019
The biochemical basis of migraine predisposition

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This chapter discusses some aspects of the biochemistry of migraine predisposition, and indicate how some of the initiating factors may interact with the central monoamine systems. Professor Lance and others have discussed persuasively how these centres (particularly the raphe nuclei and locus coeruleus) may be involved in the generation of a migraine attack. It is likely that the more we understand about individual vulnerability, the more we may be able to tailor specific treatment to particular patients.

Keywords: migraine predisposition; biochemistry; monoamine systems; raphe nuclei; migraine attack; locus coeruleus

Chapter.  8963 words.  Illustrated.

Subjects: Neuroscience

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