Chapter

NMDA receptors, neuronal development, and neurodegeneration

JOHN GARTHWAITE

in The NMDA Receptor

Second edition

Published in print February 1995 | ISBN: 9780192625021
Published online March 2012 | e-ISBN: 9780191724701 | DOI: http://dx.doi.org/10.1093/acprof:oso/9780192625021.003.0018
NMDA receptors, neuronal development, and neurodegeneration

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In several brain regions, N-methyl-d-aspartate (NMDA) receptors are specially effective during the developmental period, where they appear to play important roles in the formation and stabilization of developing synapses. The early activation of NMDA receptors could also provide signals which promote neuronal survival, growth, and differentiation. This chapter attempts to review this area of NMDA receptor research and to place the information into a chronological framework.

Keywords: neural development; NMDA receptors; neuronal survival; synapses; neuronal growth; neuronal differentiation

Chapter.  11722 words.  Illustrated.

Subjects: Neuroscience

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