7. Biochemical markers of nutrient intake

Chris J. Bates, David I. Thurnham, Sheila A. Bingham, Barrie M. Margetts and Michael Nelson

in Design Concepts in Nutritional Epidemiology

Second edition

Published in print April 1997 | ISBN: 9780192627391
Published online September 2009 | e-ISBN: 9780191723704 | DOI:
7. Biochemical markers of nutrient intake

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This chapter takes a look at the utility of biochemical measurements in different body tissues for estimating dietary exposures (as opposed to the determination of nutritional status). Validity (accuracy) and reproducibility (precision) are defined in relation to biomarkers in light of natural variations in physiological levels within and between individuals. Definitions are given of measures of nutrients in blood, urine, and other tissues, and compartments (e.g., hair, saliva, adipose tissue, finger nails, toe nails), and the feasibility of predicting intake from each measure. The chapter then describes relevant measures, nutrient by nutrient, for vitamins, minerals, lipids, protein, and energy, and the problems relating to dietary fibre.

Keywords: biomarkers; intake; validity; reproducibility; physiological variation; strengths; weaknesses

Chapter.  33998 words.  Illustrated.

Subjects: Public Health and Epidemiology

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