Chapter

<i>Tests using multiple markers</i>

Nicholas Wald and Allan Hackshaw

in Antenatal and Neonatal Screening

Second edition

Published in print November 2000 | ISBN: 9780192628268
Published online September 2009 | e-ISBN: 9780191723605 | DOI: http://dx.doi.org/10.1093/acprof:oso/9780192628268.003.0002
Tests using multiple markers

Show Summary Details

Preview

This chapter describes the methodology behind screening using multiple markers together in a single test. The method is based on estimating an individual's risk of having the disorder being screened for. This is the most efficient method for screening with multiple markers because it maximizes the detection rate for a given false-positive rate. Risk replaces component markers as the screening variable.

Keywords: screening tests; diagnostic tests; multivariate screening; multiple markers; detection rate; false-positive rate

Chapter.  11348 words.  Illustrated.

Subjects: Public Health and Epidemiology

Full text: subscription required

How to subscribe Recommend to my Librarian

Buy this work at Oxford University Press »

Users without a subscription are not able to see the full content. Please, subscribe or login to access all content.