Chapter

Sickle cell disease

Polly Edmonds

in Palliative Care for Non-cancer Patients

Published in print May 2001 | ISBN: 9780192629609
Published online November 2011 | e-ISBN: 9780191730054 | DOI: http://dx.doi.org/10.1093/acprof:oso/9780192629609.003.0011
Sickle cell disease

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Sickle cell disease (SCD) is a family of haemoglobin disorders characterised by chronic haemolysis (destruction of red blood cells), intermittent vaso-occlusion (occlusion of blood vessels), and marked variations in the character and severity of symptoms among individuals. SCD is now the second most common inherited disorder in the UK, with a prevalence of 0.23 per thousand births, and is associated with significant morbidity and mortality. This chapter reviews pathophysiology and current management strategies for SCD, the identification of patients with a poorer prognosis, and the role of palliative care in the management of these patients.

Keywords: patient care; pathophysiology; inherited disorders; disease management

Chapter.  5378 words. 

Subjects: Palliative Medicine

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