Chapter

<i>Selection of the optimal pulse sequence for functional MRI</i>

Peter A. Bandettini

in Functional Magnetic Resonance Imaging

Published in print November 2001 | ISBN: 9780192630711
Published online March 2012 | e-ISBN: 9780191724770 | DOI: http://dx.doi.org/10.1093/acprof:oso/9780192630711.003.0006
Selection of the optimal pulse sequence for functional MRI

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This chapter assists the functional magnetic resonance imaging (fMRI) user in making an informed decision regarding the choice of functional MRI pulse sequence, and presents the pulse sequence choices against a wider backdrop of relevant variables, ranging from paradigm timing to available hardware. It explores the variables that can be optimized in typical functional MRI experiments, which include: information content, sensitivity, acquisition speed, image resolution, brain coverage and anatomical image quality. Summaries and discussions of the tradeoffs regarding the variables described are also included, and some of the issues relating to selection of the possible and the optimal temporal resolution and spatial resolution in fMRI experiments are considered. The rapid rate of improvement in pulse sequence design, data processing, information content, data interpretation and paradigm design can be overwhelming to the novice and even to the advanced user. The hope is to build a broader perspective of what the limits and possibilities of fMRI are.

Keywords: magnetic resonance imaging; functional MRI; temporal resolution; spatial resolution; optimal pulse sequence

Chapter.  13707 words.  Illustrated.

Subjects: Neuroscience

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