Spatial and temporal resolution in fMRI

Ravi S. Menon and Bradley G. Goodyear

in Functional Magnetic Resonance Imaging

Published in print November 2001 | ISBN: 9780192630711
Published online March 2012 | e-ISBN: 9780191724770 | DOI:
Spatial and temporal resolution in fMRI

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This chapter addresses the limitations imposed by the functional magnetic resonance imaging (fMRI) technique and suggests some strategies to improve spatial and temporal resolution. It begins with the discussion of limits to spatial resolution in fMRI and shows that there are a number of factors to consider in achieving high spatial resolution with fMRI. The spatial resolution of the haemodynamics is also discussed. Since the haemodynamics are the source of the fMRI signal, the chapter also discusses how different sources contribute to the fMRI signal and reviews current opinion on how well localized the haemodynamic response actually is. It also reviews fMRI techniques that can be used to eliminate unwanted contributions to the measured signal and thereby increase the contrast-to-noise ratio of the fMRI signal directly related to submillimetre neural activity. Finally, the chapter shows an example of the high spatial resolution capabilities of fMRI in the human visual cortex.

Keywords: fMRI; spatial resolution; temporal resolution; haemodynamics; neural activity; visual cortex

Chapter.  9714 words.  Illustrated.

Subjects: Neuroscience

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