Chapter

<i>Begin with ‘If…’</i>

William A. Silverman

in Where's the Evidence?

Published in print April 1999 | ISBN: 9780192630889
Published online September 2009 | e-ISBN: 9780191723568 | DOI: http://dx.doi.org/10.1093/acprof:oso/9780192630889.003.0009
Begin with ‘If…’

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This chapter presents a 1989 commentary on randomized clinical trials. It argues that given the uncertainties about the wide extrapolation of results after any and all formal clinical studies, it makes sense to consider a graded approach to the release of a promising approach for everyday use. Instead of country-wide release, in a step-wise plan new treatment would be made available in only one city or other specific region in order to closely monitor the initial field experience with unselected patients.

Keywords: medical practice; medical research; randomized clinical trials; graded approach; country-wide release

Chapter.  1517 words. 

Subjects: Public Health and Epidemiology

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