Chapter

Single-center versus multicenter trials

Curtis L. Meinert and Susan Tonascia

in Clinical Trials

Published in print September 1986 | ISBN: 9780195035681
Published online September 2009 | e-ISBN: 9780199864478 | DOI: http://dx.doi.org/10.1093/acprof:oso/9780195035681.003.0004

Series: Monographs in Epidemiology and Biostatistics

Single-center versus multicenter trials

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This chapter provides a definition of single and multicenter trials and discusses a number of issues related to these two classes of trials. These include National Institutes of Health count of single center and multicenter trials, design characteristics of single center versus multicenter trials, the pros and cons of single center versus multicenter trials, initiation of single center versus multicenter trials, investigator incentives for single center versus multicenter trials, timing of incentives for single center versus multicenter trials, and cost of single center versus multicenter trials.

Keywords: clinical trials; single center trials; multicenter trials; design characteristics; investigator incentives; timing of incentives

Chapter.  3409 words. 

Subjects: Public Health and Epidemiology

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