Randomization and the mechanics of treatment masking

Curtis L. Meinert and Susan Tonascia

in Clinical Trials

Published in print September 1986 | ISBN: 9780195035681
Published online September 2009 | e-ISBN: 9780199864478 | DOI:

Series: Monographs in Epidemiology and Biostatistics

Randomization and the mechanics of treatment masking

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A valid trial requires a method for assigning patients to a test or control treatment that is free of selection bias. The best method for ensuring bias-free selection is a bona fide randomization scheme. This chapter discusses the principles and practices to be followed in administering the randomization schedule.

Keywords: clinical trials; fixed randomization; adaptive randomization; treatment assignments

Chapter.  11215 words.  Illustrated.

Subjects: Public Health and Epidemiology

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