Chapter

Molecular Mechanisms of Synaptic Function in the Hippocampus: Neurotransmitter Exocytosis and Glutamatergic, GABAergic, and Cholinergic Transmission

Osten Pavel, Wisden William and Sprengel Rolf

in The Hippocampus Book

Published in print December 2006 | ISBN: 9780195100273
Published online May 2009 | e-ISBN: 9780199864133 | DOI: http://dx.doi.org/10.1093/acprof:oso/9780195100273.003.0007

Series: Oxford Neuroscience Series

Molecular Mechanisms of Synaptic Function in the Hippocampus: Neurotransmitter Exocytosis and Glutamatergic, GABAergic, and Cholinergic Transmission

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This chapter discusses the molecular biology of hippocampal cells with particular emphasis on synaptic function. It starts by describing the basis of all signal transmission processes, the release of the signaling transmitter from the presynaptic terminal. It then details the key glutamate and GABA receptors responsible for the “nuts and bolts” of hippocampal chemical transmission. As an example of modulatory transmission, it discusses how acetylcholine muscarinic and nicotinic receptors influence information flow in the hippocampal cell types.

Keywords: excitatory transmission; inhibitory transmission; signal transmission; glutamate; GABA receptors

Chapter.  41636 words.  Illustrated.

Subjects: Neuroscience

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