Chapter

Confounding: What It Is and What Can Be Done

Ezra Susser, Sharon Schwartz, Alfredo Morabia and Evelyn J. Bromet

in Psychiatric Epidemiology

Published in print July 2006 | ISBN: 9780195101812
Published online September 2009 | e-ISBN: 9780199864096 | DOI: http://dx.doi.org/10.1093/acprof:oso/9780195101812.003.12

Series: Oxford Psychiatry Series

Confounding: What It Is and What Can Be Done

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The first part of this chapter discusses the conditions under which a factor can confound the association between exposure and disease, and the conditions under which this cannot occur. It also differentiates confounders from antecedents or mediators. The next part discusses methods devised to neutralize the effects of confounders. Two standard methods are presented: matching to prevent confounding in the data by equalizing the exposed and the unexposed on a potential confounder, and statistical adjustment to compensate for confounding in the data by separating the effects of the exposure from the effects of the confounder.

Keywords: factors; exposure; disease; confounders; cohort studies; antecedents; mediators

Chapter.  5490 words.  Illustrated.

Subjects: Public Health and Epidemiology

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